輔酶Q–細(xì)胞色素c還原酶

{{enzyme
| Name = 泛醇-細(xì)胞色素c還原酶
| EC_number = 1.10.2.2
| CAS_number = 9027-03-6
| IUBMB_EC_number = 1/10/2/2
| GO_code = 0008121
| image = Cytochrome1ntz.PNG
| width = 
| caption = 結(jié)合了[[泛醌]]的線粒體細(xì)胞色素bc1復(fù)合體晶體結(jié)構(gòu)<ref name="pmid12885240">{{PDB|1ntz}}; {{cite journal | author = Gao X, Wen X, Esser L, Quinn B, Yu L, Yu CA, Xia D | title = Structural basis for the quinone reduction in the bc1 complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc1 with bound substrate and inhibitors at the Qi site | journal = Biochemistry | volume = 42 | issue = 30 | pages = 9067–80 | year = 2003 | month = August | pmid = 12885240 | doi = 10.1021/bi0341814 | url = }}</ref>。
}}
'''[[泛醇]]—[[細(xì)胞色素]]c[[還原酶]]'''（{{lang-en|Ubiquinol-cytochrome-c reductase}}，{{EC number|1.10.2.2}}）在酶學(xué)中是指一種[[催化]]如下化學(xué)反應(yīng)的酶：

:QH<sub>2</sub> + 2 高鐵細(xì)胞色素c <math>\rightleftharpoons</math> Q + 2 亞鐵細(xì)胞色素c + 2 H<sup>+</sup>

因此，此酶的兩個(gè)[[底物]]分別是二[[氫醌]]（QH<sub>2</sub>）與高鐵（Fe<sup>3+</sup>）細(xì)胞色素c，而其三個(gè)產(chǎn)物則分別是醌（Q）、亞鐵（Fe<sup>2+</sup>）細(xì)胞色素c以及氫離子。

== 參考文獻(xiàn) ==

{{reflist|2}}

== 深入閱讀 ==

{{refbegin}}
* {{cite journal | doi = 10.1016/0005-2728(77)90099-8 | author = Marres CM, Slater EC | year = 1977 | title = Polypeptide composition of purified QH2:cytochrome c oxidoreductase from beef-heart mitochondria | journal = Biochim. Biophys. Acta.  | volume = 462 | pages = 531–548  | pmid = 597492 | issue = 3 }}
* {{cite journal | author = Rieske JS | year = 1976 | title = Composition, structure, and function of complex III of the respiratory chain | journal = Biochim. Biophys. Acta.  | volume = 456 | pages = 195–247  | pmid = 788795 | issue = 2 }}
* {{cite journal | author = Wikstrom M, Krab K, Saraste M | year = 1981 | title = Proton-translocating cytochrome complexes | journal = Annu. Rev. Biochem.  | volume = 50 | pages = 623–655  | pmid = 6267990 | doi = 10.1146/annurev.bi.50.070181.003203 }}
{{refend}}

== 外部鏈接 ==
* [http://sb20.lbl.gov/cytbc1 cytochrome ''bc''<sub>1</sub> complex site (Edward A. Berry)] at lbl.gov
* [http://www.life.uiuc.edu/crofts/bc-complex_site cytochrome ''bc''<sub>1</sub> complex site (Antony R. Crofts)] at uiuc.edu
* [http://metallo.scripps.edu/PROMISE/CYTBC1.html PROMISE Database: cytochrome ''bc''<sub>1</sub> complex] at scripps.edu
* [http://www2.ufp.pt/~pedros/anim/2frame-iiien.htm Interactive Molecular Model of Complex III] (Requires [http://www.mdl.com/products/framework/chime/ MDL Chime])
* {{UMichOPM|families|superfamily|3}} - Calculated positions of bc1 and related complexes in membranes
* {{MeshName|Coenzyme+Q-Cytochrome-c+Reductase}}

{{Diphenol family oxidoreductases}}
{{Electron transport chain}}
{{Proton pumps}}
{{Mitochondrial DNA}}

[[Category:EC 1.10.2]]

[[Category:已知結(jié)構(gòu)的酶]] [[Category:細(xì)胞呼吸]] [[Category:鐵-硫蛋白]] [[Category:內(nèi)在膜蛋白]]
==參考來(lái)源==
*[http://zh.wikipedia.org/wiki/%E8%BE%85%E9%85%B6Q%E2%80%93%E7%BB%86%E8%83%9E%E8%89%B2%E7%B4%A0c%E8%BF%98%E5%8E%9F%E9%85%B6 維基百科-輔酶Q–細(xì)胞色素c還原酶]